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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T76964 | Valanafusp alfa | ||
Valanafusp alfa (AGT-181) is a recombinant fusion protein that combines a chimeric monoclonal antibody targeting the human insulin receptor (HIR) with human iduronidase (IDUA), facilitating brain penetration. It is utili... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-00395 | Insulin Protein, Human, Recombinant | Human | P. pastoris (Yeast) |
INS (Insulin) is a Protein Coding gene. This gene encodes insulin, a peptide hormone that plays a vital role in the regulation of carbohydrate and lipid metabolism. After removal of the precursor signal peptide, proinsul... | |||
TMPY-01146 | Insulin Receptor Protein, Human, Recombinant (long isoform, His) | Human | HEK293 Cells |
Insulin Receptor Protein, Human, Recombinant (long isoform, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 107 kDa and the accession number is P06213-1. | |||
TMPY-04395 | Insulin Receptor Protein, Human, Recombinant (His & GST) | Human | Baculovirus Insect Cells |
Insulin Receptor Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 72.3 kDa and the accession number is P06213-1. | |||
TMPY-01149 | Insulin Receptor Protein, Human, Recombinant (short isoform, His) | Human | HEK293 Cells |
Insulin Receptor Protein, Human, Recombinant (short isoform, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 106 kDa and the accession number is P06213-2. | |||
TMPY-05283 | Insulin Receptor Protein, Human, Recombinant (long isoform, His), Biotinylated | Human | HEK293 Cells |
Insulin Receptor Protein, Human, Recombinant (long isoform, His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 107 kDa and the accession number is P06213-1. | |||
TMPH-02196 | TXNDC5 Protein, Human, Recombinant (GST) | Human | E. coli |
Possesses thioredoxin activity. Has been shown to reduce insulin disulfide bonds. Also complements protein disulfide-isomerase deficiency in yeast. TXNDC5 Protein, Human, Recombinant (GST) is expressed in E. coli express... | |||
TMPH-01094 | CELA2A Protein, Human, Recombinant (His) | Human | P. pastoris (Yeast) |
Elastase that enhances insulin signaling and might have a physiologic role in cellular glucose metabolism. Circulates in plasma and reduces platelet hyperactivation, triggers both insulin secretion and degradation, and i... | |||
TMPH-02197 | TXNDC5 Protein, Human, Recombinant | Human | E. coli |
Possesses thioredoxin activity. Has been shown to reduce insulin disulfide bonds. Also complements protein disulfide-isomerase deficiency in yeast. TXNDC5 Protein, Human, Recombinant is expressed in E. coli expression sy... | |||
TMPY-06479 | Cathepsin H Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Proinflammatory cytokines decreased the expression of CTSH in human islets and primary rat beta-cells, and overexpression of CTSH protected insulin-secreting cells against cytokine-induced apoptosis. Cathepsin H Protein,... | |||
TMPH-02323 | SLC30A8 Protein, Human, Recombinant (His) | Human | E. coli |
Facilitates the accumulation of zinc from the cytoplasm into intracellular vesicles, being a zinc-efflux transporter. May be a major component for providing zinc to insulin maturation and/or storage processes in insulin-... | |||
TMPH-01093 | CELA2A Protein, Human, Recombinant (E. coli, His) | Human | E. coli |
Elastase that enhances insulin signaling and might have a physiologic role in cellular glucose metabolism. Circulates in plasma and reduces platelet hyperactivation, triggers both insulin secretion and degradation, and i... | |||
TMPH-01562 | IAPP Protein, Human, Recombinant (GST) | Human | E. coli |
Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism. IAPP Protein, Human, Recombinant (GST) is expressed in E. coli expression s... | |||
TMPY-04081 | Cathepsin H Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Proinflammatory cytokines decreased the expression of CTSH in human islets and primary rat beta-cells, and overexpression of CTSH protected insulin-secreting cells against cytokine-induced apoptosis. Cathepsin H Protein,... | |||
TMPK-01354 | IGF2R Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
The cation-independent mannose-6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) is a multifunctional receptor. It is involved in a variety of cellular processes which become dysregulated in cancer. IGF2R Pro... | |||
TMPH-02022 | RXFP2 Protein, Human, Recombinant (His & Myc) | Human | E. coli |
Receptor for relaxin. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. May also be a receptor for Leydig insulin-like peptide (INSL3). RXFP2 Pro... | |||
TMPH-01385 | GLP1R Protein, Human, Recombinant (His) | Human | HEK293 Cells |
G-protein coupled receptor for glucagon-like peptide 1 (GLP-1). Ligand binding triggers activation of a signaling cascade that leads to the activation of adenylyl cyclase and increased intracellular cAMP levels. Plays a ... | |||
TMPK-01353 | IGF2R Domain 1-3 Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
The cation-independent mannose-6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) is a multifunctional receptor. It is involved in a variety of cellular processes which become dysregulated in cancer. IGF2R Dom... | |||
TMPK-01355 | IGF2R Domain 1-7 Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
The cation-independent mannose-6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) is a multifunctional receptor. It is involved in a variety of cellular processes which become dysregulated in cancer. IGF2R Dom... | |||
TMPK-01361 | IGF2R Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
The cation-independent mannose-6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) is a multifunctional receptor. It is involved in a variety of cellular processes which become dysregulated in cancer. IGF2R Pro... | |||
TMPH-01384 | GLP1R Protein, Human, Recombinant (E. coli, His) | Human | E. coli |
G-protein coupled receptor for glucagon-like peptide 1 (GLP-1). Ligand binding triggers activation of a signaling cascade that leads to the activation of adenylyl cyclase and increased intracellular cAMP levels. Plays a ... | |||
TMPH-01462 | HNRNPH1 Protein, Human, Recombinant (GST) | Human | E. coli |
This protein is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in ... | |||
TMPK-01534 | Chimeric HLA-A*02:01 (mα3) &B2M&LMP2 (CLGGLLTMV) Monomer Protein, Human&Mouse, MHC (His & Avi) | Human & Mouse | HEK293 Cells |
The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that sel... | |||
TMPK-01535 | Chimeric HLA-A*02:01 (mα3) &B2M&LMP2 (CLGGLLTMV) Tetramer Protein, Human&Mouse, MHC (His & Avi) | Human & Mouse | HEK293 Cells |
The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that sel... | |||
TMPK-01523 | Chimeric HLA-A*02:01 (mα3) &B2M&WT-1 (RMFPNAPYL) Monomer Protein, Human&Mouse, MHC (His & Avi) | Human & Mouse | HEK293 Cells |
The WT1 protein plays a role in cell growth, the process by which cells mature to perform specific functions (differentiation), and the self-destruction of cells (apoptosis). WT1 is differentially expressed in serous, en... | |||
TMPK-01522 | Chimeric HLA-A*02:01 (mα3) &B2M&WT-1 (RMFPNAPYL) Tetramer Protein, Human&Mouse, MHC (His & Avi) | Human & Mouse | HEK293 Cells |
The WT1 protein plays a role in cell growth, the process by which cells mature to perform specific functions (differentiation), and the self-destruction of cells (apoptosis). WT1 is differentially expressed in serous, en... |